AIDS Project Los Angeles - APLA - is dedicated to: improving the lives of people affected by HIV disease; reducing the incidence of HIV infection; and advocating for fair and effective HIV-related public policy. APLA offers direct services for people living with HIV/AIDS, including Benefits & Work Services, Case Management, Dental Services, Mental Health services, Necessities of Life Program free food pantries, Nutrition Education, and Treatment Education.

APLA also offers free HIV testing and HIV prevention groups and programs for African American gay men, youth, Native Americans, and people who use crystal meth.