Dr. Mandeville's clinical practice focus is cosmetic and reconstructive eye plastic surgery. This includes surgery around the eyes, including the eyelids and brows, tear ducts and orbits. He also has extensive experience in cosmetic laser surgery and Botox™ applications as well as microdermabrasion.

Dr. Mandeville has taught courses to ophthalmology residents at Massachusetts Eye & Ear Infirmary and workshop courses through the American Academy of Ophthalmology. He has published papers and review articles in a wide variety of scientific journals. His most recent research project involves the vascularization of a new enucleation implant.

Dr. Mandeville is on staff at the Massachusetts Eye & Ear Infirmary, South Shore Hospital, Quincy Medical Center, Milton Hospital, Brockton Hospital, Caritas Carney Hospital, Caritas Good Samaritan Medical Center and Cape Cod.